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Prevalence of Epistasis in the Evolution of Influenza A Surface Proteins
The surface proteins of human influenza A viruses experience positive selection to escape both human immunity and, more recently, antiviral drug treatments. In bacteria and viruses, immune-escape and drug-resistant phenotypes often appear through a combination of several mutations that have epistati...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040651/ https://ncbi.nlm.nih.gov/pubmed/21390205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001301 |
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