Allele-specific nonstationarity in evolution of influenza A virus surface proteins

Influenza A virus (IAV) is a major public health problem and a pandemic threat. Its evolution is largely driven by diversifying positive selection so that relative fitness of different amino acid variants changes with time due to changes in herd immunity or genomic context, and novel amino acid vari...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Popova, Anfisa V., Safina, Ksenia R., Ptushenko, Vasily V., Stolyarova, Anastasia V., Favorov, Alexander V., Neverov, Alexey D., Bazykin, Georgii A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800338/
https://ncbi.nlm.nih.gov/pubmed/31578251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904246116
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