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Multigene predictors of tacrolimus exposure in kidney transplant recipients
AIM: Determine the effect of the genetic variants beyond CYP3A5*3 on tacrolimus disposition. PATIENTS & METHODS: We studied genetic correlates of tacrolimus trough concentrations with POR*28, CYP3A4*22 and ABCC2 haplotypes in a large, ethnically diverse kidney transplant cohort (n = 2008). RESUL...
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| 出版年: | Pharmacogenomics |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Future Medicine Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4527535/ https://ncbi.nlm.nih.gov/pubmed/26067485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.15.42 |
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