B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis

RATIONALE: B cells contribute to atherosclerosis through subset specific mechanisms. Whereas some controversy exists about the role of B-2 cells, B-1a cells are atheroprotective due to secretion of atheroprotective IgM antibodies independent of antigen. B-1b cells, a unique subset of B-1 cells that...

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Udgivet i:Circ Res
Main Authors: Rosenfeld, Sam M., Perry, Heather M., Gonen, Ayelet, Prohaska, Thomas A., Srikakulapu, Prasad, Grewal, Sukhdeep, Das, Deepanjana, McSkimming, Chantel, Taylor, Angela M., Tsimikas, Sotirios, Bender, Timothy P., Witztum, Joseph L., McNamara, Coleen A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527334/
https://ncbi.nlm.nih.gov/pubmed/26082558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.306044
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