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Protective role for B1b B cells and IgM in obesity-associated inflammation, glucose intolerance, and insulin resistance

OBJECTIVE: Little is known regarding the role(s) B cells play in obesity-induced metabolic dysfunction. The present study utilized a mouse with B cell-specific deletion of Id3 (Id3(Bcell KO)) to identify B cell functions involved in the metabolic consequences of obesity. APPROACH AND RESULTS: Diet-i...

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Detaylı Bibliyografya
Yayımlandı:Arterioscler Thromb Vasc Biol
Asıl Yazarlar: Harmon, Daniel B., Srikakulapu, Prasad, Kaplan, Jennifer L., Oldham, Stephanie N., McSkimming, Chantel, Garmey, James, Perry, Heather M., Kirby, Jennifer L., Prohaska, Thomas A., Gonen, Ayelet, Hallowell, Peter, Schirmer, Bruce, Tsimikas, Sotirios, Taylor, Angela M., Witztum, Joseph L., McNamara, Coleen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808436/
https://ncbi.nlm.nih.gov/pubmed/26868208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307166
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