B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis

RATIONALE: B cells contribute to atherosclerosis through subset specific mechanisms. Whereas some controversy exists about the role of B-2 cells, B-1a cells are atheroprotective due to secretion of atheroprotective IgM antibodies independent of antigen. B-1b cells, a unique subset of B-1 cells that...

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Publié dans:Circ Res
Auteurs principaux: Rosenfeld, Sam M., Perry, Heather M., Gonen, Ayelet, Prohaska, Thomas A., Srikakulapu, Prasad, Grewal, Sukhdeep, Das, Deepanjana, McSkimming, Chantel, Taylor, Angela M., Tsimikas, Sotirios, Bender, Timothy P., Witztum, Joseph L., McNamara, Coleen A.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527334/
https://ncbi.nlm.nih.gov/pubmed/26082558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.306044
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