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β-Catenin destruction complex-independent regulation of Hippo–YAP signaling by APC in intestinal tumorigenesis
Mutations in Adenomatous polyposis coli (APC) underlie familial adenomatous polyposis (FAP), an inherited cancer syndrome characterized by the widespread development of colorectal polyps. APC is best known as a scaffold protein in the β-catenin destruction complex, whose activity is antagonized by c...
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| Publicado en: | Genes Dev |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526734/ https://ncbi.nlm.nih.gov/pubmed/26193883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.264515.115 |
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