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Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP
The Hippo signaling pathway converges on YAP to regulate growth, differentiation, and regeneration. Previous studies with overexpressed proteins have shown that YAP is phosphorylated by its upstream kinase, Lats1/2, on multiple sites, including an evolutionarily conserved 14-3-3-binding site whose p...
में बचाया:
| में प्रकाशित: | Genes Dev |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cold Spring Harbor Laboratory Press
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495399/ https://ncbi.nlm.nih.gov/pubmed/26109051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.264234.115 |
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