Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP

The Hippo signaling pathway converges on YAP to regulate growth, differentiation, and regeneration. Previous studies with overexpressed proteins have shown that YAP is phosphorylated by its upstream kinase, Lats1/2, on multiple sites, including an evolutionarily conserved 14-3-3-binding site whose p...

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Bibliografski detalji
Izdano u:Genes Dev
Glavni autori: Chen, Qian, Zhang, Nailing, Xie, Rui, Wang, Wei, Cai, Jing, Choi, Kyung-Suk, David, Karen Kate, Huang, Bo, Yabuta, Norikazu, Nojima, Hiroshi, Anders, Robert A., Pan, Duojia
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495399/
https://ncbi.nlm.nih.gov/pubmed/26109051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.264234.115
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