The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

Although a developmental role for Hippo signaling in organ size control is well appreciated, how this pathway functions in tissue regeneration is largely unknown. Here we address this issue using a dextran sodium sulfate (DSS)-induced colonic regeneration model. We find that regenerating crypts expr...

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Detalhes bibliográficos
Main Authors: Cai, Jing, Zhang, Nailing, Zheng, Yonggang, de Wilde, Roeland F., Maitra, Anirban, Pan, Duojia
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964748/
https://ncbi.nlm.nih.gov/pubmed/21041407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1978810
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