Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

Cerebral cavernous malformations 2 (CCM2) loss is associated with the familial form of CCM disease. The protein kinase MEKK3 (MAP3K3) is essential for embryonic angiogenesis in mice and interacts physically with CCM2, but how this interaction is mediated and its relevance to cerebral vasculature are...

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Опубликовано в: :Nat Commun
Главные авторы: Fisher, Oriana S., Deng, Hanqiang, Liu, Dou, Zhang, Ya, Wei, Rong, Deng, Yong, Zhang, Fan, Louvi, Angeliki, Turk, Benjamin E., Boggon, Titus J., Su, Bing
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526114/
https://ncbi.nlm.nih.gov/pubmed/26235885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8937
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