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Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology
Cerebral cavernous malformations (CCM) are neurovascular dysplasias that result in mulberry-shaped lesions predominantly located in brain and spinal tissues. Mutations in three genes are associated with CCM. These genes encode for the proteins KRIT1/CCM1 (krev interaction trapped 1/cerebral cavernou...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Basel
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3999170/ https://ncbi.nlm.nih.gov/pubmed/24287896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1532-9 |
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