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Cerebral cavernous malformation proteins at a glance

Loss-of-function mutations in genes encoding KRIT1 (also known as CCM1), CCM2 (also known as OSM and malcavernin) or PDCD10 (also known as CCM3) cause cerebral cavernous malformations (CCMs). These abnormalities are characterized by dilated leaky blood vessels, especially in the neurovasculature, th...

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Detalhes bibliográficos
Main Authors: Draheim, Kyle M., Fisher, Oriana S., Boggon, Titus J., Calderwood, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924200/
https://ncbi.nlm.nih.gov/pubmed/24481819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.138388
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