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A combined optogenetic-knockdown strategy reveals a major role of tomosyn in mossy fiber synaptic plasticity

Neurotransmitter release probability (P(r)) largely determines the dynamic properties of synapses. While much is known on the role of presynaptic proteins in transmitter release, their specific contribution to synaptic plasticity is unclear. One such protein, tomosyn, is believed to reduce P(r) by i...

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Библиографические подробности
Опубликовано в: :Cell Rep
Главные авторы: Ben-Simon, Yoav, Rodenas-Ruano, Alma, Alviña, Karina, Lam, Alice D., Stuenkel, Edward L., Castillo, Pablo E., Ashery, Uri
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525481/
https://ncbi.nlm.nih.gov/pubmed/26166572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.037
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