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A combined optogenetic-knockdown strategy reveals a major role of tomosyn in mossy fiber synaptic plasticity

Neurotransmitter release probability (P(r)) largely determines the dynamic properties of synapses. While much is known on the role of presynaptic proteins in transmitter release, their specific contribution to synaptic plasticity is unclear. One such protein, tomosyn, is believed to reduce P(r) by i...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Ben-Simon, Yoav, Rodenas-Ruano, Alma, Alviña, Karina, Lam, Alice D., Stuenkel, Edward L., Castillo, Pablo E., Ashery, Uri
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525481/
https://ncbi.nlm.nih.gov/pubmed/26166572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.037
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