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A combined optogenetic-knockdown strategy reveals a major role of tomosyn in mossy fiber synaptic plasticity

Neurotransmitter release probability (P(r)) largely determines the dynamic properties of synapses. While much is known on the role of presynaptic proteins in transmitter release, their specific contribution to synaptic plasticity is unclear. One such protein, tomosyn, is believed to reduce P(r) by i...

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Vydáno v:Cell Rep
Hlavní autoři: Ben-Simon, Yoav, Rodenas-Ruano, Alma, Alviña, Karina, Lam, Alice D., Stuenkel, Edward L., Castillo, Pablo E., Ashery, Uri
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525481/
https://ncbi.nlm.nih.gov/pubmed/26166572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.037
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