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A combined optogenetic-knockdown strategy reveals a major role of tomosyn in mossy fiber synaptic plasticity

Neurotransmitter release probability (P(r)) largely determines the dynamic properties of synapses. While much is known on the role of presynaptic proteins in transmitter release, their specific contribution to synaptic plasticity is unclear. One such protein, tomosyn, is believed to reduce P(r) by i...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Rep
Hauptverfasser: Ben-Simon, Yoav, Rodenas-Ruano, Alma, Alviña, Karina, Lam, Alice D., Stuenkel, Edward L., Castillo, Pablo E., Ashery, Uri
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525481/
https://ncbi.nlm.nih.gov/pubmed/26166572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.037
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