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Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid, and energy homeostasis in mice
Tbc1d1 is a Rab GTPase-activating protein (GAP) implicated in regulating intracellular retention and cell surface localization of the glucose transporter GLUT4 and thus glucose uptake in a phosphorylation-dependent manner. Tbc1d1 is most abundant in skeletal muscle but is expressed at varying levels...
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| izdano v: | Am J Physiol Endocrinol Metab |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525116/ https://ncbi.nlm.nih.gov/pubmed/26015432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00007.2015 |
| Oznake: |
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