AT(1)R blockade in adverse milieus: role of SMRT and corepressor complexes

ANG II type 1 receptor blockade (AT(1)R-BLK) is used extensively to slow down the progression of proteinuric kidney diseases. We hypothesized that AT(1)R-BLK provides podocyte protection through regulation of silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and vitamin D recep...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Singh, Tejinder, Ayasolla, Kamesh, Rai, Partab, Chandel, Nirupama, Haque, Shabirul, Lederman, Rivka, Husain, Mohammad, Vethantham, Vasupradha, Chawla, Amrita, Vashistha, Himanshu, Saleem, Moin A., Ding, Guohua, Chander, Praveen N., Malhotra, Ashwani, Meggs, Leonard G., Singhal, Pravin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525095/
https://ncbi.nlm.nih.gov/pubmed/26084932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00476.2014
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