Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension

Prolonged vasoconstrictor-stimulated phospholipase C activity can induce arterial constriction, hypertension, and smooth muscle hypertrophy/hyperplasia. Arrestin proteins are recruited by agonist-occupied G protein-coupled receptors to terminate signaling and counteract changes in vascular tone. Her...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Willets, Jonathon M., Nash, Craig A., Rainbow, Richard D., Nelson, Carl P., Challiss, R. A. John
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525080/
https://ncbi.nlm.nih.gov/pubmed/25972452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00079.2015
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