Arrestins 2 and 3 differentially regulate ET(A) and P2Y(2) receptor-mediated cell signaling and migration in arterial smooth muscle

Overstimulation of endothelin type A (ET(A)) and nucleotide (P2Y) Gα(q)-coupled receptors in vascular smooth muscle causes vasoconstriction, hypertension, and, eventually, hypertrophy and vascular occlusion. G protein-coupled receptor kinases (GRKs) and arrestin proteins are sequentially recruited b...

Full description

Saved in:
Bibliographic Details
Main Authors: Morris, Gavin E., Nelson, Carl P., Brighton, Paul J., Standen, Nicholas B., Challiss, R. A. John, Willets, Jonathon M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311302/
https://ncbi.nlm.nih.gov/pubmed/22159081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00202.2011
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items