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Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2
AIMS: Prolonged endothelin (ET) receptor signalling causes vasoconstriction and can lead to hypertension, vascular smooth muscle hypertrophy, and hyperplasia. Usually, G protein-coupled receptor signalling is negatively regulated by G protein-coupled receptor kinases (GRKs), preventing prolonged or...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802200/ https://ncbi.nlm.nih.gov/pubmed/19748906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp310 |
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