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Giant protein kinases: domain interactions and structural basis of autoregulation.

The myosin-associated giant protein kinases twitchin and titin are composed predominantly of fibronectin- and immunoglobulin-like modules. We report the crystal structures of two autoinhibited twitchin kinase fragments, one from Aplysia and a larger fragment from Caenorhabditis elegans containing an...

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Detalhes bibliográficos
Main Authors: Kobe, B, Heierhorst, J, Feil, S C, Parker, M W, Benian, G M, Weiss, K R, Kemp, B E
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452506/
https://ncbi.nlm.nih.gov/pubmed/9003756
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