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Structural basis and prediction of substrate specificity in protein serine/threonine kinases
The large number of protein kinases makes it impractical to determine their specificities and substrates experimentally. Using the available crystal structures, molecular modeling, and sequence analyses of kinases and substrates, we developed a set of rules governing the binding of a heptapeptide su...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140887/ https://ncbi.nlm.nih.gov/pubmed/12502784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0134224100 |
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