Structural basis and prediction of substrate specificity in protein serine/threonine kinases
The large number of protein kinases makes it impractical to determine their specificities and substrates experimentally. Using the available crystal structures, molecular modeling, and sequence analyses of kinases and substrates, we developed a set of rules governing the binding of a heptapeptide su...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12502784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0134224100 |
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