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Structural basis and prediction of substrate specificity in protein serine/threonine kinases

The large number of protein kinases makes it impractical to determine their specificities and substrates experimentally. Using the available crystal structures, molecular modeling, and sequence analyses of kinases and substrates, we developed a set of rules governing the binding of a heptapeptide su...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Brinkworth, Ross I., Breinl, Robert A., Kobe, Bostjan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC140887/
https://ncbi.nlm.nih.gov/pubmed/12502784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0134224100
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