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The structural basis of integrin-linked kinase–PINCH interactions
The heterotrimeric complex between integrin-linked kinase (ILK), PINCH, and parvin is an essential signaling platform, serving as a convergence point for integrin and growth-factor signaling and regulating cell adhesion, spreading, and migration. We report a 1.6-Å crystal structure of the ILK ankyri...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634877/ https://ncbi.nlm.nih.gov/pubmed/19074270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811415106 |
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