Purification and SAXS Analysis of the Integrin Linked Kinase, PINCH, Parvin (IPP) Heterotrimeric Complex

The heterotrimeric protein complex containing the integrin linked kinase (ILK), parvin, and PINCH proteins, termed the IPP complex, is an essential component of focal adhesions, where it interacts with many proteins to mediate signaling from integrin adhesion receptors. Here we conduct a biochemical...

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Bibliographic Details
Main Authors: Stiegler, Amy L., Grant, Thomas D., Luft, Joseph R., Calderwood, David A., Snell, Edward H., Boggon, Titus J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561323/
https://ncbi.nlm.nih.gov/pubmed/23383235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055591
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