Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation

Kindlins are essential FERM-domain-containing focal adhesion (FA) proteins required for proper integrin activation and signaling. Despite the widely accepted importance of each of the three mammalian kindlins in cell adhesion, the molecular basis for their function has yet to be fully elucidated, an...

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Bibliographic Details
Main Authors: Huet-Calderwood, Clotilde, Brahme, Nina N., Kumar, Nikit, Stiegler, Amy L., Raghavan, Srikala, Boggon, Titus J., Calderwood, David A.
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179494/
https://ncbi.nlm.nih.gov/pubmed/25086068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.155879
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