Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation

Kindlins are essential FERM-domain-containing focal adhesion (FA) proteins required for proper integrin activation and signaling. Despite the widely accepted importance of each of the three mammalian kindlins in cell adhesion, the molecular basis for their function has yet to be fully elucidated, an...

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Bibliografiske detaljer
Main Authors: Huet-Calderwood, Clotilde, Brahme, Nina N., Kumar, Nikit, Stiegler, Amy L., Raghavan, Srikala, Boggon, Titus J., Calderwood, David A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179494/
https://ncbi.nlm.nih.gov/pubmed/25086068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.155879
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