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Improved oral absorption of cilostazol via sulfonate salt formation with mesylate and besylate
OBJECTIVE: Cilostazol is a Biopharmaceutical Classification System class II drug with low solubility and high permeability, so its oral absorption is variable and incomplete. The aim of this study was to prepare two sulfonate salts of cilostazol to increase the dissolution and hence the oral bioavai...
Gardado en:
| Publicado en: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Dove Medical Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524531/ https://ncbi.nlm.nih.gov/pubmed/26251575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S87687 |
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