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Dioxin receptor regulates aldehyde dehydrogenase to block melanoma tumorigenesis and metastasis
BACKGROUND: The dioxin (AhR) receptor can have oncogenic or tumor suppressor activities depending on the phenotype of the target cell. We have shown that AhR knockdown promotes melanoma primary tumorigenesis and lung metastasis in the mouse and that human metastatic melanomas had reduced AhR levels...
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| Gepubliceerd in: | Mol Cancer |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524442/ https://ncbi.nlm.nih.gov/pubmed/26242870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0419-9 |
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