Proteasome Inhibition Induces Nuclear Translocation and Transcriptional Activation of the Dioxin Receptor in Mouse Embryo Primary Fibroblasts in the Absence of Xenobiotics

The aryl hydrocarbon receptor (AHR) is a transcription factor that is highly conserved during evolution and shares important structural features with the Drosophila developmental regulators Sim and Per. Although much is known about the mechanism of AHR activation by xenobiotics, little information i...

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Autori principali: Santiago-Josefat, Belen, Pozo-Guisado, Eulalia, Mulero-Navarro, Sonia, Fernandez-Salguero, Pedro M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Nucleocytoplasmic Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86716/
https://ncbi.nlm.nih.gov/pubmed/11238907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1700-1709.2001
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