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Cellular Transformation of Mouse Embryo Fibroblasts in the Absence of Activator E2Fs

The E2F family of transcription factors, broadly divided into activator and repressor E2Fs, regulates cell cycle genes. Current models indicate that activator E2Fs are necessary for cell cycle progression and tumorigenesis and are also required to mediate transformation induced by DNA tumor viruses....

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Gupta, Tushar, Sáenz Robles, Maria Teresa, Pipas, James M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403490/
https://ncbi.nlm.nih.gov/pubmed/25717106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03578-14
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