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Cellular Transformation of Mouse Embryo Fibroblasts in the Absence of Activator E2Fs

The E2F family of transcription factors, broadly divided into activator and repressor E2Fs, regulates cell cycle genes. Current models indicate that activator E2Fs are necessary for cell cycle progression and tumorigenesis and are also required to mediate transformation induced by DNA tumor viruses....

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Gupta, Tushar, Sáenz Robles, Maria Teresa, Pipas, James M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403490/
https://ncbi.nlm.nih.gov/pubmed/25717106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03578-14
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