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Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis

The aryl hydrocarbon receptor (AhR) has roles in cell proliferation, differentiation and organ homeostasis, including the liver. AhR depletion induces undifferentiation and pluripotency in normal and transformed cells. Here, AhR-null mice (AhR−/−) were used to explore whether AhR controls liver rege...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moreno-Marín, Nuria, Barrasa, Eva, Morales-Hernández, Antonio, Paniagua, Beroé, Blanco-Fernández, Gerardo, Merino, Jaime M., Fernández-Salguero, Pedro M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5585208/
https://ncbi.nlm.nih.gov/pubmed/28874739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10984-w
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