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HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death.

The mechanisms by which apoptosis is prevented by survival factors are largely unknown. Using an interaction cloning approach, we identified a protein that binds to the intracellular domain of the hepatocyte growth factor (HGF) receptor. This protein was identified as BAG-1, a recently characterized...

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Autori principali: Bardelli, A, Longati, P, Albero, D, Goruppi, S, Schneider, C, Ponzetto, C, Comoglio, P M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC452442/
https://ncbi.nlm.nih.gov/pubmed/8947043
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