The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells

Although the retinoblastoma-susceptibility gene RB1 is inactivated in a wide range of human tumours, in colorectal cancer, the retinoblastoma protein (Rb) function is often preserved and the RB locus even amplified. Importantly, we have previously shown that Rb interacts with the anti-apoptotic Bcl-...

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Detalhes bibliográficos
Main Authors: Collard, T J, Urban, B C, Patsos, H A, Hague, A, Townsend, P A, Paraskeva, C, Williams, A C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481130/
https://ncbi.nlm.nih.gov/pubmed/23059827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.142
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