Transcriptional down-regulation of the retinoblastoma protein is associated with differentiation and apoptosis in human colorectal epithelial cells

The aim of this study was to investigate the regulation of Rb protein expression in relation to increased differentiation and induction of apoptosis in colonic epithelial cells. In vivo, Rb protein expression was found to be down-regulated towards the top of the normal colonic crypt, coincident with...

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Sonraí Bibleagrafaíochta
Main Authors: Guy, M, Moorghen, M, Bond, J A, Collard, T J, Paraskeva, C, Williams, A C
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2001
Ábhair:
Regular Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363755/
https://ncbi.nlm.nih.gov/pubmed/11207048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1635
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