Transcriptional down-regulation of the retinoblastoma protein is associated with differentiation and apoptosis in human colorectal epithelial cells

The aim of this study was to investigate the regulation of Rb protein expression in relation to increased differentiation and induction of apoptosis in colonic epithelial cells. In vivo, Rb protein expression was found to be down-regulated towards the top of the normal colonic crypt, coincident with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guy, M, Moorghen, M, Bond, J A, Collard, T J, Paraskeva, C, Williams, A C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2001
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363755/
https://ncbi.nlm.nih.gov/pubmed/11207048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1635
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