The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cells

Although the retinoblastoma-susceptibility gene RB1 is inactivated in a wide range of human tumours, in colorectal cancer, the retinoblastoma protein (Rb) function is often preserved and the RB locus even amplified. Importantly, we have previously shown that Rb interacts with the anti-apoptotic Bcl-...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Collard, T J, Urban, B C, Patsos, H A, Hague, A, Townsend, P A, Paraskeva, C, Williams, A C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481130/
https://ncbi.nlm.nih.gov/pubmed/23059827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.142
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