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The Anti-Apoptotic Activity of BAG3 Is Restricted by Caspases and the Proteasome

BACKGROUND: Caspase-mediated cleavage and proteasomal degradation of ubiquitinated proteins are two independent mechanisms for the regulation of protein stability and cellular function. We previously reported BAG3 overexpression protected ubiquitinated clients, such as AKT, from proteasomal degradat...

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Bibliografische gegevens
Hoofdauteurs: Virador, Victoria M., Davidson, Ben, Czechowicz, Josephine, Mai, Alisha, Kassis, Jareer, Kohn, Elise C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662420/
https://ncbi.nlm.nih.gov/pubmed/19352495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005136
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