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Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells

During HIV-1 assembly, the Gag viral proteins are targeted and assemble at the inner leaflet of the cell plasma membrane. This process could modulate the cortical actin cytoskeleton, located underneath the plasma membrane, since actin dynamics are able to promote localized membrane reorganization. I...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Thomas, Audrey, Mariani-Floderer, Charlotte, López-Huertas, Maria Rosa, Gros, Nathalie, Hamard-Péron, Elise, Favard, Cyril, Ohlmann, Theophile, Alcamí, José, Muriaux, Delphine
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524266/
https://ncbi.nlm.nih.gov/pubmed/26018170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00469-15
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