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Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells

During HIV-1 assembly, the Gag viral proteins are targeted and assemble at the inner leaflet of the cell plasma membrane. This process could modulate the cortical actin cytoskeleton, located underneath the plasma membrane, since actin dynamics are able to promote localized membrane reorganization. I...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Thomas, Audrey, Mariani-Floderer, Charlotte, López-Huertas, Maria Rosa, Gros, Nathalie, Hamard-Péron, Elise, Favard, Cyril, Ohlmann, Theophile, Alcamí, José, Muriaux, Delphine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524266/
https://ncbi.nlm.nih.gov/pubmed/26018170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00469-15
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