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Role of Gag and lipids during HIV-1 assembly in CD4(+) T cells and macrophages
HIV-1 is an RNA enveloped virus that preferentially infects CD4(+) T lymphocytes and also macrophages. In CD4(+) T cells, HIV-1 mainly buds from the host cell plasma membrane. The viral Gag polyprotein targets the plasma membrane and is the orchestrator of the HIV assembly as its expression is suffi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4069574/ https://ncbi.nlm.nih.gov/pubmed/25009540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00312 |
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