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Self assembly of HIV-1 Gag protein on lipid membranes generates PI(4,5)P(2)/Cholesterol nanoclusters
The self-assembly of HIV-1 Gag polyprotein at the inner leaflet of the cell host plasma membrane is the key orchestrator of virus assembly. The binding between Gag and the plasma membrane is mediated by specific interaction of the Gag matrix domain and the PI(4,5)P(2) lipid (PIP(2)). It is unknown w...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5180241/ https://ncbi.nlm.nih.gov/pubmed/28008947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39332 |
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