Differential Impact of In Vivo CD8(+) T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques

Numerous studies have demonstrated that CD8(+) T lymphocytes suppress virus replication during human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection. However, the mechanisms underlying this activity of T cells remain incompletely understood. Here, we conducted CD8(+) T lym...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Chowdhury, Ankita, Hayes, Timothy L., Bosinger, Steven E., Lawson, Benton O., Vanderford, Thomas, Schmitz, Joern E., Paiardini, Mirko, Betts, Michael, Chahroudi, Ann, Estes, Jacob D., Silvestri, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524088/
https://ncbi.nlm.nih.gov/pubmed/26063417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00869-15
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