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Contacts-based prediction of binding affinity in protein–protein complexes

Almost all critical functions in cells rely on specific protein–protein interactions. Understanding these is therefore crucial in the investigation of biological systems. Despite all past efforts, we still lack a thorough understanding of the energetics of association of proteins. Here, we introduce...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vangone, Anna, Bonvin, Alexandre MJJ
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523921/
https://ncbi.nlm.nih.gov/pubmed/26193119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07454
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