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Contacts-based prediction of binding affinity in protein–protein complexes

Almost all critical functions in cells rely on specific protein–protein interactions. Understanding these is therefore crucial in the investigation of biological systems. Despite all past efforts, we still lack a thorough understanding of the energetics of association of proteins. Here, we introduce...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Vangone, Anna, Bonvin, Alexandre MJJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523921/
https://ncbi.nlm.nih.gov/pubmed/26193119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07454
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