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Contacts-based prediction of binding affinity in protein–protein complexes

Almost all critical functions in cells rely on specific protein–protein interactions. Understanding these is therefore crucial in the investigation of biological systems. Despite all past efforts, we still lack a thorough understanding of the energetics of association of proteins. Here, we introduce...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Vangone, Anna, Bonvin, Alexandre MJJ
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523921/
https://ncbi.nlm.nih.gov/pubmed/26193119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07454
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