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Contacts-based prediction of binding affinity in protein–protein complexes

Almost all critical functions in cells rely on specific protein–protein interactions. Understanding these is therefore crucial in the investigation of biological systems. Despite all past efforts, we still lack a thorough understanding of the energetics of association of proteins. Here, we introduce...

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Publicat a:eLife
Autors principals: Vangone, Anna, Bonvin, Alexandre MJJ
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523921/
https://ncbi.nlm.nih.gov/pubmed/26193119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07454
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