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Sensitivity of mRNA Translation

Using the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, elongation, and termination rates along the mRNA strand on the steady-state protein translation rate. We show that the sensitivity of m...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Poker, Gilad, Margaliot, Michael, Tuller, Tamir
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523843/
https://ncbi.nlm.nih.gov/pubmed/26238363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12795
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