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Sensitivity of mRNA Translation

Using the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, elongation, and termination rates along the mRNA strand on the steady-state protein translation rate. We show that the sensitivity of m...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Poker, Gilad, Margaliot, Michael, Tuller, Tamir
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523843/
https://ncbi.nlm.nih.gov/pubmed/26238363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12795
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