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Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product.
The retinoblastoma gene product, pRb, negatively regulates cell proliferation by modulating the activity of the transcription factor E2F1 that controls expression of S-phase genes. To dissect transcriptional regulation of E2F1 by pRb, we developed a means to control the subcellular localization of p...
Shranjeno v:
| izdano v: | EMBO J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
1996
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8918469/ |
| Oznake: |
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